Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Jan;15(1):20-6.

Clinical and course indicators of bipolar disorder type I with and without opioid dependence

Amir Shabani  1 , Atefeh Ghanbari Jolfaei, Hajar Ahmadi Vazmalaei, Azizeh Afkham Ebrahimi, Morteza Naserbakht
Affiliations

Clinical and course indicators of bipolar disorder type I with and without opioid dependence

Amir Shabani et al. J Res Med Sci. 2010 Jan.

Abstract

Background: The existing evidence about the clinical situations of the bipolar patients with opioid dependence is scarce. The present study was carried out to compare the clinical features and course of the bipolar disorder type I regarding the two subgroups of opioid dependent and non-dependent.

Methods: There were 178 adult patients with bipolar disorder type I consecutively referred to the Iran Hospital of Psychiatry, Tehran, Iran, from January 2008 to January 2009 who enrolled in the study. The Persian Structured Clinical Interview for DSM-IV axis I disorders (SCID-I), HDRS-17, and Y-MRS were administered for all patients. Other clinical information was gathered through the face-to-face interviews with the probands and the hospital records. The T test, Chi square test and logistic regression were used to analyze the data.

Results: The mean age of probands were 33.6 ± 11.1 years old and they were mostly male. Among the evaluated indices, the factors gender, anxiety disorders comorbidity, non-adherence, and positive family history were different significantly and independently from the other studied factors between opioid dependent and non-dependent bipolar patients.

Conclusions: Despite some differences, the opioid dependent and non-dependent bipolar patients did not have any significant difference regarding most of the examined clinical and course indices.

Keywords: Bipolar Disorder; Opioid; Outcome; Substance Abuse; Substance Dependence.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest

Authors have no conflict of interests.

References

    1. Baldassano CF. Illness course, comorbidity, gender, and suicidality in patients with bipolar disorder. J Clin Psychiatry. 2006;67(Suppl 11):8–11. - PubMed
    1. Maremmani I, Perugi G, Pacini M, Akiskal HS. Toward a unitary perspective on the bipolar spectrum and substance abuse: opiate addiction as a paradigm. J Affect Disord. 2006;93(1-3):1–12. - PubMed
    1. Cerullo MA, Strakowski SM. The prevalence and significance of substance use disorders in bipolar type I and II disorder. Subst Abuse Treat Prev Policy. 2007;2:29. - PMC - PubMed
    1. Arabgol F, Alaghband Rad J, Sharifi V, Hakim Shoushtari M, Shaabani A, Davari Ashtiani R, et al. Reliability of a Persian translation of the Composite International Diagnostic Interview (CIDI), section for substance use disorders: in a multi-center study in Iran. Advances in Cognitive Science. 2005;7(2):38–45. (Persian)
    1. Levin FR, Hennessy G. Bipolar disorder and substance abuse. Biol Psychiatry. 2004;56(10):738–48. - PubMed

LinkOut - more resources