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. 2011 Apr 21;17(15):2013-8.
doi: 10.3748/wjg.v17.i15.2013.

Effect of multidisciplinary team treatment on outcomes of patients with gastrointestinal malignancy

Chang-Zheng Du  1 , Jie Li, Yong Cai, Ying-Shi Sun, Wei-Cheng Xue, Jin Gu
Affiliations

Effect of multidisciplinary team treatment on outcomes of patients with gastrointestinal malignancy

Chang-Zheng Du et al. World J Gastroenterol. .

Abstract

Aim: To evaluate the effect of multidisciplinary team (MDT) treatment modality on outcomes of patients with gastrointestinal malignancy in China.

Methods: Data about patients with gastric and colorectal cancer treated in our center during the past 10 years were collected and divided into two parts. Part 1 consisted of the data collected from 516 consecutive complicated cases discussed at MDT meetings in Peking University School of Oncology (PKUSO) from December 2005 to July 2009. Part 2 consisted of the data collected from 263 consecutive cases of resectable locally advanced rectal cancer from January 2001 to January 2005. These 263 patients were divided into neoadjuvant therapy (NT) group and control group. Patients in NT group received MDT treatment, namely neoadjuvant therapy + surgery + postoperative adjuvant therapy. Patients in control group underwent direct surgery + postoperative adjuvant therapy. The outcomes in two groups were compared.

Results: The treatment strategy was altered after discussed at MDT meeting in 76.81% of gastric cancer patients and in 58.33% of colorectal cancer patients before operation. The sphincter-preservation and local control of tumor were better in NT group than in control group. The 5-year overall survival rate was also higher in NT group than in control group (77.23% vs 69.75%, P = 0.049).

Conclusion: MDT treatment modality can significantly improve the outcomes of patients with gastrointestinal malignancy in China.

Keywords: Multidisciplinary team; Neoadjuvant radiotherapy; Prognosis; Rectal cancer.

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Figures

Figure 1
Figure 1
Disease-free survival rate (A) and overall survival rate (B) for patients in two groups. MDT: Multidisciplinary team.
See this image and copyright information in PMC

References

    1. Carter S, Garside P, Black A. Multidisciplinary team working, clinical networks, and chambers; opportunities to work differently in the NHS. Qual Saf Health Care. 2003;12 Suppl 1:i25–i28. - PMC - PubMed
    1. Fleissig A, Jenkins V, Catt S, Fallowfield L. Multidisciplinary teams in cancer care: are they effective in the UK? Lancet Oncol. 2006;7:935–943. - PubMed
    1. Moehler M, Lyros O, Gockel I, Galle PR, Lang H. Multidisciplinary management of gastric and gastroesophageal cancers. World J Gastroenterol. 2008;14:3773–3780. - PMC - PubMed
    1. Forrest LM, McMillan DC, McArdle CS, Dunlop DJ. An evaluation of the impact of a multidisciplinary team, in a single centre, on treatment and survival in patients with inoperable non-small-cell lung cancer. Br J Cancer. 2005;93:977–978. - PMC - PubMed
    1. Junor EJ, Hole DJ, Gillis CR. Management of ovarian cancer: referral to a multidisciplinary team matters. Br J Cancer. 1994;70:363–370. - PMC - PubMed