Review
doi: 10.2533/chimia.2011.168.
Access to macrocycles with an endo aryl ether and an endo aryl-aryl bond, development and application
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- PMID: 21528652
- DOI: 10.2533/chimia.2011.168
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Review
Access to macrocycles with an endo aryl ether and an endo aryl-aryl bond, development and application
Chimia (Aarau).
2011.
Free article
Abstract
Macrocyclization methodologies allowing access to macrocycles having an endo aryl ether and an endo aryl-aryl bond, especially those based on an intramolecular S(N)Ar reaction and the Suzuki-Miyaura reaction, are summarized. Total synthesis of complestatin, a bis-macrocyclic natural product, featuring these two technologies are presented.
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