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. 2011 May;17(5):907-9.
doi: 10.3201/eid1705.100968.

Genomic characterization of Nipah virus, West Bengal, India

Vidya A Arankalle  1 , Bhaswati T Bandyopadhyay, Ashwini Y Ramdasi, Ramesh Jadi, Dilip R Patil, Mehebubar Rahman, Monalisa Majumdar, Parthasarthi S Banerjee, Amiyakumar K Hati, Ramaprasad P Goswami, Dhruba Kumar Neogi, Akhilesh C Mishra
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Genomic characterization of Nipah virus, West Bengal, India

Vidya A Arankalle et al. Emerg Infect Dis. 2011 May.

Abstract

An intrafamilial outbreak in West Bengal, India, involving 5 deaths and person-to-person transmission was attributed to Nipah virus. Full-genome sequence of Nipah virus (18,252 nt) amplified from lung tissue showed 99.2% nt and 99.8% aa identity with the Bangladesh-2004 isolate, suggesting a common source of the virus.

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Figures

Figure
Figure
A) Phylogenetic analysis based on partial nucleocapsid (N) gene nucleotide sequences (159 nt, according to Nipah virus [NiV] Bangladesh sequence, GenBank accession no. AY988601, 168–327 nt) of the 4 NiVs sequenced during this study (boldface). Five sequences of the viruses from Siliguri (8) and from representative NiV sequences obtained from GenBank indicated by the respective accession numbers. Values at different nodes denote bootstrap support. B) Full genome–based phylogenetic analysis of the NiV sequenced from the lung tissue of a patient (boldface). Representative NiV sequences obtained from GenBank are indicated by the respective accession numbers. Values at different nodes denote bootstrap support. Scale bars indicate nucleotide substitutions per site.
See this image and copyright information in PMC

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