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. 2011 May;17(5):910-3.
doi: 10.3201/eid1705.101873.

Chikungunya virus, southeastern France

Affiliations

Chikungunya virus, southeastern France

Marc Grandadam et al. Emerg Infect Dis. 2011 May.

Abstract

In September 2010, autochthonous transmission of chikungunya virus was recorded in southeastern France, where the Aedes albopictus mosquito vector is present. Sequence analysis of the viral genomes of imported and autochthonous isolates indicated new features for the potential emergence and spread of the virus in Europe.

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Figures

Figure
Figure
Phylogenetic relationships among chikungunya virus isolates from cases of chikungunya fever in France, based on complete E2-6K-E1 nucleotide sequence (2,771 nt) analysis. Gray shading indicates imported and autochthonous strains. Sequence alignments were performed by using BioNumerics version 5.1 (www.applied-maths.com). Phylogenetic analysis was inferred by using the maximum-likelihood method as implemented in MEGA version 5 software (www.megasoftware.net). Bootstrap support values (1,000 replicates) are indicated at major nodes. The sequence of the strains from France described in this study has been deposited in GenBank (accession number pending); other sequences were retrieved from GenBank. Scale bar indicates number of base substitutions per site. ECSA, east/central/south Asia.

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