doi: 10.1128/mcb.10.1.382-386.1990.
Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes
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- PMID: 2152964
- PMCID: PMC360760
- DOI: 10.1128/mcb.10.1.382-386.1990
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Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes
Mol Cell Biol.
1990 Jan.
Abstract
We describe the structure of the major germ line RNA transcribed from unrearranged immunoglobulin alpha heavy-chain genes in immunoglobulin M-expressing cells of the I.29 mu B-cell lymphoma, a cell line capable of switching to immunoglobulin A expression upon lipopolysaccharide treatment. This germ line alpha RNA has a small open reading frame that does not include the C alpha domain, and this RNA appears to be present on polysomes in I.29 mu cells.
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