Translational control by the eukaryotic ribosome
- PMID: 21529706
- DOI: 10.1016/j.cell.2011.04.006
Translational control by the eukaryotic ribosome
Abstract
The ribosome plays a universally conserved role in catalyzing protein synthesis. Kondrashov et al. (2011) now provide evidence that the loss of function of ribosomal protein L38 in mice leads to a selective reduction in the translation of Hox mRNAs, thus suggesting that ribosomal proteins play a critical role during embryonic development.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning.Cell. 2011 Apr 29;145(3):383-397. doi: 10.1016/j.cell.2011.03.028. Cell. 2011. PMID: 21529712 Free PMC article.
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