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. 2010 May;15(5):295-302.

Invasive group A streptococcal disease: Management and chemoprophylaxis

[Article in English, French]
Ud Allen, Dl Moore

Invasive group A streptococcal disease: Management and chemoprophylaxis

[Article in English, French]
Ud Allen et al. Paediatr Child Health. 2010 May.

Abstract
in English, French

Given the potentially devastating consequences of severe invasive group A streptococcal disease, attention has been directed toward the role of chemoprophylaxis and the optimization of management strategies. In response to this issue, Canadian guidelines were previously developed. However, the uptake of these recommendations is variable across Canada. The present document summarizes key components of the recommendations for use by Canadian physicians. The importance of penicillin in the treatment of group A streptococcal disease is reaffirmed, and the role of clindamycin is discussed. In addition, in situations in which chemoprophylaxis may be considered, the preferred agents are summarized.

Étant donné les conséquences au potentiel dévastateur d’une grave infection à streptocoque envahissante du groupe A, les auteurs se sont intéressés au rôle de la chimioprophylaxie et à l’optimisation des stratégies de prise en charge. À cet égard, des lignes directrices canadiennes ont déjà été mises en œuvre. Cependant, leur application est variable au Canada. Le présent document résume les principaux éléments des recommandations que doivent respecter les médecins canadiens. L’importance de la pénicilline dans le traitement de l’infection à streptocoque du groupe A est confirmée, et le rôle de la clindamycine est abordé. De plus, dans des situations où la chimioprophylaxie peut être envisagée, on fait la synthèse des antibiotiques à favoriser.

Keywords: Chemoprophylaxis; Group A streptococcus; Necrotizing fasciitis; Toxic shock.

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