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Case Reports
. 2011 Mar 23:2:36.
doi: 10.4103/2152-7806.78246.

Neurocytoma of the cerebellum

Hideki Ogiwara  1 , Steve Dubner, Eileen Bigio, James Chandler
Affiliations
Case Reports

Neurocytoma of the cerebellum

Hideki Ogiwara et al. Surg Neurol Int. .

Abstract

Background: Neurocytomas are benign central nervous system tumor composed of small cells with characteristics of neuronal differentiation; they are usually located in the supratentorial periventricular region, in close relation to the septum pellucidum and the foramen of Monro.

Case description: Herein we report a rare case of a neurocytoma located in the cerebellar hemisphere. To date there are only four such reported cases.

Conclusion: Neurocytomas should be considered in the differential diagnosis of mass lesions in the cerebellum.

Keywords: Cerebellar hemisphere; neurocytoma; posterior fossa.

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Figures

Figure 1
Figure 1
(a) Magnetic resonance imaging demonstrating the tumor in the right cerebellar hemisphere as a hypointense lesion in a T1-weighted image (b) and as a enhancing lesion in a gadolinium T1-weighted image
Figure 2
Figure 2
Histology slides. (a) Intraoperative smear (×400) showing discohesive cells with minimal cytoplasm and neurocytic nuclei with speckled chromatin. (b) (H and E, ×100) showing cells with small, round nuclei, minimal pleomorphism and no mitotic activity. Perivascular acellular zones and scattered intratumoral acellular zones, reminiscent of Homer-Wright rosettes were noted. (c) Ki67 immunostain (×100) showing a very low proliferation index <1%. (d) Synaptophysin immunostain (×100) showing diffuse positivity
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