Case Reports
doi: 10.1093/ndt/gfr224.
Epub 2011 May 4.
AA amyloidosis associated with hepatitis B
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- PMID: 21543651
- DOI: 10.1093/ndt/gfr224
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Case Reports
AA amyloidosis associated with hepatitis B
Nephrol Dial Transplant.
2011 Jul.
Abstract
We report a 13-year-old Indian boy with nephrotic syndrome caused by renal AA amyloidosis. Workup of the AA amyloidosis revealed chronic hepatitis B. Laser microdissection of the Congo-red-positive glomeruli and vessels followed by liquid chromatography and tandem mass spectrometry confirmed the presence of serum amyloid A (SAA) protein and ruled out hereditary and familial amyloidosis. Furthermore, mass spectrometry also detected a variant of SAA protein (SAA W71R).
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