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Case Reports
. 2011 Jul;26(7):2407-12.
doi: 10.1093/ndt/gfr224. Epub 2011 May 4.

AA amyloidosis associated with hepatitis B

Abhijeet Saha  1 , Jason D Theis, Julie A Vrana, Nand K Dubey, Vineeta V Batra, Sanjeev Sethi
Affiliations
Case Reports

AA amyloidosis associated with hepatitis B

Abhijeet Saha et al. Nephrol Dial Transplant. 2011 Jul.

Abstract

We report a 13-year-old Indian boy with nephrotic syndrome caused by renal AA amyloidosis. Workup of the AA amyloidosis revealed chronic hepatitis B. Laser microdissection of the Congo-red-positive glomeruli and vessels followed by liquid chromatography and tandem mass spectrometry confirmed the presence of serum amyloid A (SAA) protein and ruled out hereditary and familial amyloidosis. Furthermore, mass spectrometry also detected a variant of SAA protein (SAA W71R).

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