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Case Reports
. 2010 Apr;2(2):60-1.
doi: 10.4161/derm.2.2.13503.

Methylmalonic aciduria presenting with recurrent multiple molluscum contagiosum lesions

Motonobu Nakamura  1 , Yoshiki Tokura
Affiliations
Case Reports

Methylmalonic aciduria presenting with recurrent multiple molluscum contagiosum lesions

Motonobu Nakamura et al. Dermatoendocrinol. 2010 Apr.

Abstract

Methylmalonic aciduria is a rare metabolic disorder with autosomal recessive inheritance. Patients with methylmalonic aciduria develop a variety of skin manifestations: superficial scalded skin lesions, alopecia, psoriasiform eruptions, acrodermatitis enteropathica-like lesions, fulminant ecthyma gangrenosum and ichthyosis. We report a Japanese boy, diagnosed with methylmalonic aciduria, who suffered from recurrent multiple molluscum lesions around the eyes.

Keywords: immunodeficiency; methylmalonic acidemia; methylmalonic aciduria; molluscum contagiosum; skin.

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Figures

Figure 1
Figure 1
Multiple discrete solid skin-colored papules around the both inner canthi.
See this image and copyright information in PMC

References

    1. Obenholzer VG, Levin B, Burgess EA, et al. Methylmalonic aciduria. An inborn error of metabolism leading to chronic metabolic acidosis. Arch Dis Child. 1967;42:492–504. - PMC - PubMed
    1. Bodemer C, De Prost Y, Bachollet B, et al. Cutaneous manifestations of methymalonic and propionic academia: a description based on 38 cases. Br J Dermatol. 1994;131:93–98. - PubMed
    1. Howard R, Frieden IJ, Crawford D, et al. Methylmalonic acidemia, cobalamin c type, presenting with cutaneous manifestations. Arch Dermatol. 1997;133:1563–1566. - PubMed
    1. Okano M, Kishiyama K, Satake N, et al. A case of fulminant ecthyma gangrenosum associated with Pseudomonas aeruginosa infection in a patient with methylmalonic acidemia. Scand J Infect Dis. 1994;26:107–108. - PubMed
    1. Boggio P, Machado MC, De Oliveira ZN, et al. Methylmalonic acidemia presenting with an ichthyosis vulgaris-like aspect. Pediatr Dermatol. 2007;24:455–456. - PubMed

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