Dextromethorphan sites, sigma receptors, and the psychotomimetic effects of sigma opiates
- PMID: 2154766
Dextromethorphan sites, sigma receptors, and the psychotomimetic effects of sigma opiates
Abstract
A review of the literature shows that the dysphoric and psychotomimetic side effects of opiate agonist-antagonist reside in the opiate levorotatory isomer. Thus, the current definition of the sigma receptor cannot explain the psychotomimetic effects of sigma opiates.