The ammonium sulfate activation of phosphorylase b
- PMID: 2155134
- DOI: 10.1016/0014-5793(90)80627-u
The ammonium sulfate activation of phosphorylase b
Erratum in
- FEBS Lett 1990 May 7;264(1):159
Abstract
The ammonium sulfate activation of phosphorylase b has been studied. Ammonium sulfate, when present in high concentrations, induces properties of phosphorylase a in phosphorylase b, such as an enhanced affinity for AMP, a reversal of the glucose-6-P inhibition and enzyme tetramerization. The data are consistent with the interpretation that sulfates bind to the Ser-14 site and the sulfate-protein interactions at this site are responsible for activation of phosphorylase b.
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