Review
The relationship of plasminogen activators and oncogenes to tumour invasion
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- PMID: 2155139
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Review
The relationship of plasminogen activators and oncogenes to tumour invasion
Eur J Surg Oncol.
1990 Feb.
Abstract
Accruing evidence suggests an association between increased activity of plasminogen activators and transformed cells, and urokinase activity with tumour aggressiveness. The PIP2 pathway seems to provide a link between oncogene-associated transformation, cellular proliferation, plasminogen-activator expression and tumour invasion and metastasis.
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