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Review
. 1990 Feb;16(1):54-9.

The relationship of plasminogen activators and oncogenes to tumour invasion

J S Gelister  1 , P B Boulos, P J Gaffney, M Mahmoud, M R Lewin
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  • PMID: 2155139
Review

The relationship of plasminogen activators and oncogenes to tumour invasion

J S Gelister et al. Eur J Surg Oncol. 1990 Feb.

Abstract

Accruing evidence suggests an association between increased activity of plasminogen activators and transformed cells, and urokinase activity with tumour aggressiveness. The PIP2 pathway seems to provide a link between oncogene-associated transformation, cellular proliferation, plasminogen-activator expression and tumour invasion and metastasis.

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