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Case Reports
. 2011 Jan;28(1):25-7.
doi: 10.4103/0970-9371.76945.

Cytodiagnosis of coexistent cryptococcal and mycobacterial lymphadenitis in a case of AIDS

Affiliations
Case Reports

Cytodiagnosis of coexistent cryptococcal and mycobacterial lymphadenitis in a case of AIDS

Arti R Anvikar et al. J Cytol. 2011 Jan.

Abstract

Multiple infections are a common feature of acquired immunodeficiency syndrome (AIDS), but coexistent infections at the same site are rare. In this report, we describe a 35-year-old human immunodeficiency virus infected male with coexistent cryptococcal and mycobacterial lymphadenitis. He presented with generalised lymphadenopathy. Fine needle aspiration cytology of enlarged cervical lymph node, aided by special stains, revealed coexistent cryptococcal and mycobacterial infection. Coexistent infections pose diagnostic problems in AIDS patients and are likely to be missed. Special stains are valuable for accurate diagnosis of coexistent infections.

Keywords: Acquired immunodeficiency syndrome; coexistent infection; cryptococcal infection; human immunodeficiency virus; tuberculosis.

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Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
Photomicrograph showing epithelioid granuloma and caseous necrosis with cryptococci in the background (H and E, ×400)
Figure 2
Figure 2
Silver stain highlighting the cryptococci (Gomori's methanamine silver stain, ×400)
Figure 3
Figure 3
Smear showing the carminophilic capsule of cryptococci (Mucicarmine stain, ×400)
Figure 4
Figure 4
Smear showing acid fast bacillus (Ziehl Neelsen stain, ×1000)

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References

    1. Kumarguru BN, Kulkarni MH, Kamakeri NS. FNAC of peripheral lymph nodes in HIV positive patients. Sci Med. 2009;1:4–12.
    1. Suchita S, Sheeladevi CS, Sunila R, Manjunath GV. Fine needle aspiration diagnosis of cryptococcal lymphadenitis: A window of opportunity. J Cytol. 2008;25:147–9.
    1. Jayaram G, Chew MT. Fine needle aspiration cytology of lymph nodes in HIV-infected individuals. th Acta Cytol. 2000;44:960–6. - PubMed
    1. Khawcharoenporn T, Apisarnthanarak A, Sakonlaya D, Mundy LM, Bailey TC. Dual infection with Mycobacterium tuberculosis and Pneumocystis jiroveci Lymphadenitis in a Patient with HIV infection: case report and review of the literature. AIDS Patient Care STDS. 2006;20:1–5. - PubMed
    1. Rawat D, Capoor MR, Nair D, Deb M, Aggarwal P. Concomitant TB and cryptococcosis in HIV-infected patients. Trop Doct. 2008;38:251–2. - PubMed

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