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. 2008;3(11):1747-1750.

New Drimane Sesquiterpenoids from Tidestromia oblongifolia

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New Drimane Sesquiterpenoids from Tidestromia oblongifolia

Sandeep Chaudhary et al. Nat Prod Commun. 2008.

Abstract

From an acetone extract of the aerial parts of Tidestromia oblongifolia (Amaranthaceae), a new drimane sesquiterpenoid bearing an 11,12,13-trihydroxydrimene skeleton (1) as well as the 11,12 acetonide of 1 were isolated. Three known stigmastane triterpenoids were also isolated. Structures were elucidated with the aid of 1D and 2D NMR spectroscopic techniques. The absolute configuration of 1 was confirmed by single-crystal x-ray crystallography. This is the first report on phytochemical constituents from any plant of the genus Tidestromia and is the first report of the occurrence of drimanes in the Amaranthaceae.

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Figures

Figure 1
Figure 1
Structures of Compounds 1 and 2
Figure 2
Figure 2
ORTEP drawing of compound 1.
Figure 3
Figure 3
Structures of polygodial (3) and compound 4.

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