Comparative Study
doi: 10.1016/0042-6822(90)90215-d.
A porcine rotavirus strain with dual VP7 serotype specificity
Affiliations
- PMID: 2155514
- DOI: 10.1016/0042-6822(90)90215-d
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Comparative Study
A porcine rotavirus strain with dual VP7 serotype specificity
Virology.
1990 Mar.
Abstract
Porcine rotavirus MDR-13, which on original isolation showed a two-way antigenic relationship with human rotavirus RV-3, shows VP7 relationships with serotype G5 as well as G3 viruses upon gene reassortment. Analysis of porcine MDR-13 and the MD-UK reassortant revealed marked nucleotide and amino acid similarity of VP7 genes of these viruses with those of both serotype G3 and G5 viruses. Evolution of such a strain, possibly by sequential mutations in the VP7 gene, is discussed.
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