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Comparative Study
. 1990 Mar;175(1):319-22.
doi: 10.1016/0042-6822(90)90215-d.

A porcine rotavirus strain with dual VP7 serotype specificity

H S Nagesha  1 , J Huang, C P Hum, I H Holmes
Affiliations
Comparative Study

A porcine rotavirus strain with dual VP7 serotype specificity

H S Nagesha et al. Virology. 1990 Mar.

Abstract

Porcine rotavirus MDR-13, which on original isolation showed a two-way antigenic relationship with human rotavirus RV-3, shows VP7 relationships with serotype G5 as well as G3 viruses upon gene reassortment. Analysis of porcine MDR-13 and the MD-UK reassortant revealed marked nucleotide and amino acid similarity of VP7 genes of these viruses with those of both serotype G3 and G5 viruses. Evolution of such a strain, possibly by sequential mutations in the VP7 gene, is discussed.

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