Lobar distribution of cerebral microbleeds: the Rotterdam Scan Study
- PMID: 21555643
- DOI: 10.1001/archneurol.2011.93
Lobar distribution of cerebral microbleeds: the Rotterdam Scan Study
Abstract
Objective: To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds.
Design: Population-based, cross-sectional analysis.
Setting: The Rotterdam Scan Study.
Participants: A total of 198 persons (age range, 61-95 years) with lobar microbleeds.
Main outcome measures: Distribution of microbleeds over different lobes.
Results: We found that lobar cerebral microbleeds occurred significantly more often in the temporal lobe, a region known to be more affected in cerebral amyloid angiopathy.
Conclusion: This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.
Comment in
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Microbleeds and lacunar infarcts in the Rotterdam Scan Study.Arch Neurol. 2011 Oct;68(10):1344; author reply 1344-5. doi: 10.1001/archneurol.2011.230. Arch Neurol. 2011. PMID: 21987555 No abstract available.
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