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. 2011 Jun 3;13(11):2936-9.
doi: 10.1021/ol2009939. Epub 2011 May 10.

Iron-catalyzed cycloaddition of alkynenitriles and alkynes

Brendan R D'Souza  1 , Timothy K Lane, Janis Louie
Affiliations

Iron-catalyzed cycloaddition of alkynenitriles and alkynes

Brendan R D'Souza et al. Org Lett. .

Abstract

The combination of Fe(OAc)(2) and an electron-donating, sterically hindered pyridyl bisimine ligand catalyzes the cycloaddition of alkynenitriles and alkynes. A variety of substituted pyridines were obtained in good yields.

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