doi: 10.1021/ja202959n.
Epub 2011 May 11.
Enantioselective synthesis of highly substituted furans by a copper(II)-catalyzed cycloisomerization-indole addition reaction
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- PMID: 21561153
- DOI: 10.1021/ja202959n
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Enantioselective synthesis of highly substituted furans by a copper(II)-catalyzed cycloisomerization-indole addition reaction
J Am Chem Soc.
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Erratum in
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Correction to "Enantioselective Synthesis of Highly Substituted Furans by a Copper(II)-Catalyzed Cycloisomerization-Indole Addition Reaction".J Am Chem Soc. 2022 Aug 3;144(30):13981. doi: 10.1021/jacs.2c06800. Epub 2022 Jul 19. J Am Chem Soc. 2022. PMID: 35853616 No abstract available.
Abstract
A catalytic enantioselective reaction based on a copper(II) catalyst strictly containing chiral anionic ligands is described. In the present work, copper(II)-phosphate catalyst promotes the intramolecular heterocyclization of 2-(1-alkynyl)-2-alkene-1-ones and facilitates high levels of enantioselectivity in the subsequent nucleophile attack. Mechanistic studies suggest that formation of a copper(II)-indole species is important for catalysis.
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