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. 2011 Jun 21;47(23):6629-31.
doi: 10.1039/c1cc11205h. Epub 2011 May 12.

Detection of DNA base variation and cytosine methylation at a single nucleotide site using a highly sensitive fluorescent probe

Jean-Louis H A Duprey  1 , Zheng-yun Zhao, Dario M Bassani, Jack Manchester, Joseph S Vyle, James H R Tucker
Affiliations

Detection of DNA base variation and cytosine methylation at a single nucleotide site using a highly sensitive fluorescent probe

Jean-Louis H A Duprey et al. Chem Commun (Camb). .

Abstract

A fluorescent DNA probe containing an anthracene group attached via an anucleosidic linker can identify all four DNA bases at a single site as well as the epigenetic modification C/5-MeC via a hybridisation sensing assay.

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