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Review
. 2011 May;14(5):435-40.
doi: 10.3779/j.issn.1009-3419.2011.05.10.

[The EML4-ALK fusion gene in NSCLC and the clinical progress]

[Article in Chinese]
Di Wu  1 , Hong Yu
Affiliations
Review

[The EML4-ALK fusion gene in NSCLC and the clinical progress]

[Article in Chinese]
Di Wu et al. Zhongguo Fei Ai Za Zhi. 2011 May.
No abstract available

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Figures

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1
EML4-ALK融合基因结构示意图。EML4-ALK融合发生在ALK外显子20附近，在结构上能与之融合的EML4的相应的外显子的位置如箭头所示。CC：coiled-coil域；HELP：疏水的EMAP (棘皮动物微管-相关蛋白)样蛋白域；WD：WD重复区；Kinase：ALK的酪氨酸激酶域 Structure of EML4-ALK fusion gene. The corresponding positions of exons(e) of EML4 can be fused in-frame to exon 20 of ALK are indicated by arrows. CC, coiled-coil domain; HELP, hydrophobic EMAP (echinoderm microtubule-associated protein) like protein domain; WD, WD repeats; Kinase, Tyrosine kinase domain of ALK
See this image and copyright information in PMC

References

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