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Comment
. 2011 May 17;20(5):573-4.
doi: 10.1016/j.devcel.2011.04.015.

Parsing p53 Transactivation

Judith Campisi  1
Affiliations
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Parsing p53 Transactivation

Judith Campisi. Dev Cell. .

Abstract

Two functions of p53 are undisputed. Biologically, p53 is a potent tumor suppressor, whereas biochemically, it is a robust transcriptional activator of numerous target genes. Are these biological and biochemical functions of p53 related? The surprising answer, recently reported by Brady et al. (2011) in Cell, is minimally.

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