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Case Reports
. 2011 Jan;4(1):58-60.
doi: 10.4103/0974-2077.79199.

Laugier-hunziker syndrome: a rare cause of oral and acral pigmentation

Silonie Sachdeva  1 , Shabina Sachdeva, Pranav Kapoor
Affiliations
Case Reports

Laugier-hunziker syndrome: a rare cause of oral and acral pigmentation

Silonie Sachdeva et al. J Cutan Aesthet Surg. 2011 Jan.

Abstract

Laugier-Hunziker syndrome (LHS) is an acquired, benign pigmentary skin condition involving oral cavity including lower lip in the form of brown black macules 1-5 mm in size, frequently associated with longitudinal melanonychia. There is no underlying systemic abnormality or malignant predisposition associated with LHS, and therefore the prognosis is good. Important differential diagnoses include Peutz Jeghers syndrome and Addison's disease among other causes of oral and acral pigmentation. Treatment is sought mainly for cosmetic reasons and Q-switched Nd-Yag laser/ Q-switched alexandrite therapy and cryosurgery have been tried with varying success.

Keywords: Benign; longitudinal melanonychia; oral pigmentation.

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Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
(a) Pigmentation on the lower lip
Figure 1
Figure 1
(b) Pigmentation on the tongue
Figure 1
Figure 1
(c) brownish – black pigmentation on tips of fingers
Figure 1
Figure 1
(d) brownish – black pigmentation on tips of toes
Figure 2
Figure 2
Longitudinal melanonychia of thumb nails
Figure 3
Figure 3
Biopsy of a pigmented macule reveals an increase in melanin in the basal layer of the epidermis (H and E, ×100)“
See this image and copyright information in PMC

References

    1. Koch SE, LeBoit PE, Odom RB. Laugier–Hunziker syndrome. J Am Acad Dermatol. 1987;16:431–4. - PubMed
    1. Kanwar AJ, Kaur S, Kaur C, Thami GP. Laugier–Hunziker syndrome. J Dermatol. 2001;28:54–7. - PubMed
    1. Ajith C, Handa S. Laugier–Hunziker pigmentation. Indian J Dermatol Venereol Leprol. 2005;71:354–6. - PubMed
    1. Sardana K, Mishra D, Garg V. Laugier Hunziker syndrome. Indian Pediatr. 2006;43:998–1000. - PubMed
    1. Gerbig AW, Hunziker T. Idiopathic lenticular mucocutaneous pigmentation or Laugier–Hunziker syndrome with atypical features. Arch Dermatol. 1996;132:844–5. - PubMed

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