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. 2011 Jan;56(1):54-8.
doi: 10.4103/0019-5154.77554.

Nephrogenic systemic fibrosis: a brief review

Rajesh Waikhom  1 , Abhijit Taraphder
Affiliations

Nephrogenic systemic fibrosis: a brief review

Rajesh Waikhom et al. Indian J Dermatol. 2011 Jan.

Abstract

Nephrogenic systemic fibrosis is a fibrosing disorder of the skin that develops in patients with advanced renal failure. It mostly presents with progressive hardening or induration of the skin of the extremities. Systemic involvement is also known to occur in this entity. Exposure to gadolinium contrast for radiological evaluation has been identified as the offending agent. The condition is progressive and can be seriously disabling. Therapeutic options are limited and not rewarding in majority of the cases. Awareness of this entity is important so that proper precautionary measures can be taken at the earliest to ameliorate the condition.

Keywords: Nephrogenic systemic fibrosis; gadolinium; renal failure.

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Conflict of interest statement

Conflict of Interest: Nil.

Figures

Figure 1
Figure 1
Cumulative risk model created by Swaminathan and Shah[8]
See this image and copyright information in PMC

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