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. 2009 Sep 5;65(Pt 10):o2342-3.
doi: 10.1107/S1600536809035077.

Diethyl 2,6-dimethyl-4-p-tolyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate

Diethyl 2,6-dimethyl-4-p-tolyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate

Hoong-Kun Fun et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

In the title compound, C(20)H(25)NO(4), the 1,4-dihydro-pyridine ring adopts a flattened-boat conformation and forms a dihedral angle of 89.77 (8)° with the benzene ring. Inter-molecular N-H⋯O hydrogen bonds result in the formation of extended chains parallel to the b axis.

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Figures

Fig. 1.
Fig. 1.
The molecular structure of (I), showing 50% probability displacement ellipsoids and the atom numbering scheme.
Fig. 2.
Fig. 2.
Partial unit cell contents for (I) highlighting the formation of supramolecular chains mediated by N-H···O hydrogen bonding (shown as dashed lines).

References

    1. Bai, M.-S., Chen, Y.-Y., Niu, D.-L. & Peng, L. (2009). Acta Cryst. E65, o799. - PMC - PubMed
    1. Böcker, R. H. & Guengerich, F. P. (1986). J. Med. Chem.28, 1596–1603. - PubMed
    1. Boeyens, J. C. A. (1978). J. Cryst. Mol. Struct.8, 317–320.
    1. Bruker (2005). APEX2, SAINT and SADABS Bruker AXS Inc., Madison, Wisconsin, USA.
    1. Cooper, K., Fray, M. J., Parry, M. J., Richardson, K. & Steele, J. (1992). J. Med. Chem.35, 3115–3129. - PubMed