Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Dec;28(3):767-71.
doi: 10.1128/JVI.28.3.767-771.1978.

Genomic stability of gibbon oncornavirus

L Sun, T G Kawakami, S I Matoba

Genomic stability of gibbon oncornavirus

L Sun et al. J Virol. 1978 Dec.

Abstract

The 70S RNAs from several gibbon type C viruses were examined for sequence homology by molecular hybridization using complementary DNA probes. The sequence homology was found to vary with each virus isolate. The genome from one isolate was examined for genomic stability after the virus was experimentally passaged through three unrelated gibbons. The genomic homology remained unchanged after three passages, having greater than 93% homology based on complementary DNA-70S RNA hybridization and melting temperature analysis of the duplex. The genome from another isolate was similarly found to be unchanged after the virus was naturally transmitted in gibbons. The genomic variation found in the various isolates is not the consequence of recent horizontal transmission from a common virus.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Nat New Biol. 1972 Feb 9;235(58):170-1 - PubMed
    1. Biochim Biophys Acta. 1971 Jul 29;240(4):522-31 - PubMed
    1. Nat New Biol. 1972 Jan 12;235(54):35-40 - PubMed
    1. J Virol. 1974 Jul;14(1):56-67 - PubMed
    1. Proc Natl Acad Sci U S A. 1973 Dec;70(12):3316-20 - PubMed

Publication types

LinkOut - more resources