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. 2008 Oct 25;64(Pt 11):o2211-2.
doi: 10.1107/S1600536808034624.

4-Chloro-2-((1R)-1-{[(R)-(2-chloro-phen-yl)(cyclo-pent-yl)meth-yl]amino}eth-yl)phenol

Guang-You Zhang, Ting Yang, Bao-Wang Xu, Di-Juan Chen, Wan-Hui Wang

4-Chloro-2-((1R)-1-{[(R)-(2-chloro-phen-yl)(cyclo-pent-yl)meth-yl]amino}eth-yl)phenol

Guang-You Zhang et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

The title compound, C(20)H(23)Cl(2)NO, was prepared by condensation of (R)-1-(2-chloro-phen-yl)-1-cyclo-pentyl-methanamine with 1-(5-chloro-2-hydroxy-phen-yl)ethanone, resulting in the formation of a new chiral center. The structural analysis confirms the absolute configuration of the title compound and the formation of the (R,R) diastereoisomer. There is an intra-molecular O-H⋯N hydrogen bond which stabilizes the conformation of the mol-ecule. The mol-ecules are linked to each other through weak C-H⋯π inter-actions.

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Figures

Fig. 1.
Fig. 1.
Molecular view of (I) with the atom-labeling scheme. Displacement ellipsoids are drawn at the 30% probability level. H atoms are shown as small spheres of arbitrary radii. H bond is shown as dashed line.
See this image and copyright information in PMC

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