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Review
. 1990 Mar;15(3):98-102.
doi: 10.1016/0968-0004(90)90192-e.

Okadaic acid: a new probe for the study of cellular regulation

P Cohen  1 , C F Holmes, Y Tsukitani
Affiliations
Review

Okadaic acid: a new probe for the study of cellular regulation

P Cohen et al. Trends Biochem Sci. 1990 Mar.

Abstract

The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible phosphorylation of proteins.

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