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. 1990 Apr;175(2):581-5.
doi: 10.1016/0042-6822(90)90445-w.

Multiple sequence elements in the U3 region of the leukemogenic murine retrovirus SL3-2 contribute to cell-dependent gene expression

H Y Dai  1 , M Etzerodt, A J Baekgaard, S Lovmand, P Jørgensen, N O Kjeldgaard, F S Pedersen
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Multiple sequence elements in the U3 region of the leukemogenic murine retrovirus SL3-2 contribute to cell-dependent gene expression

H Y Dai et al. Virology. 1990 Apr.

Abstract

Determination of the U3 sequence of the leukemogenic murine retrovirus SL3-2 revealed close relationships to SL3-3, Akv, and Gross passage A viruses. The SL3-2 and Akv regions showed wide differences in their relative transcriptional activity in four cell lines as determined by U3-driven transient expression assays. The U3 regions of SL3-2 and SL3-3 gave rise to similar but not identical levels of expression. Deletion mapping of the SL3-2 U3 region points to several determinants of expression of different relative importance in the cell lines tested.

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