N-Cyclo-hexyl-3-(4-hydr-oxy-6-oxo-1,6-dihydro-pyrimidin-5-yl)-3-p-tolyl-propanamide
- PMID: 21581918
- PMCID: PMC2968226
- DOI: 10.1107/S1600536809001251
N-Cyclo-hexyl-3-(4-hydr-oxy-6-oxo-1,6-dihydro-pyrimidin-5-yl)-3-p-tolyl-propanamide
Abstract
In the mol-ecule of the title compound, C(20)H(25)N(3)O(3), the aromatic rings are oriented at a dihedral angle of 88.36 (3)°. The cyclo-hexane ring adopts a chair conformation. In the crystal structure, inter-molecular N-H⋯O and O-H⋯N hydrogen bonds link the mol-ecules. C-H⋯π inter-actions are also present.
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References
-
- Allen, F. H., Kennard, O., Watson, D. G., Brammer, L., Orpen, A. G. & Taylor, R. (1987). J. Chem. Soc. Perkin Trans. 2, pp. S1–19.
-
- Bruker (1998). SMART, SAINT and SADABS Bruker AXS Inc., Madison, Wisconsin, USA.
-
- Cremer, D. & Pople, J. A. (1975). J. Am. Chem. Soc.97, 1354–1358.
-
- Erian, A. W. (1993). Chem. Rev.93, 1991–2005.
-
- Janeba, Z., Balzarini, J., Andrei, G., Snoeck, R., De Clercq, E. & Robins, M. J. (2005). J. Med. Chem.48, 4690–4696. - PubMed
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