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. 2009 Jul 22;65(Pt 8):o1945.
doi: 10.1107/S1600536809028025.

1'-Methyl-2,2''-dioxoindoline-3-spiro-2'-pyrrolidine-3'-spiro-3''-indoline-4',4'-di-carbonitrile

P Ramesh, S S Sundaresan, N Vidhya Lakshmi, Paramasivan T Perumal, M N Ponnuswamy

1'-Methyl-2,2''-dioxoindoline-3-spiro-2'-pyrrolidine-3'-spiro-3''-indoline-4',4'-di-carbonitrile

P Ramesh et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

In the title compound, C(21)H(15)N(5)O(2), the pyrrolidine ring adopts a twist conformation. Both the oxindole rings are planar [maximum deviations of 0.076 (1) and 0.029 (1) Å in the two rings] and are oriented at a dihedral angle of 72.7 (1)°. The crystal structure is stabilized by C-H⋯O, N-H⋯O, N-H⋯N and C-H⋯π inter-actions.

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Figures

Fig. 1.
Fig. 1.
Perspective view of the molecule showing the displacement ellipsoids at the 50% probability level. The H atoms are shown as small circles of arbitrary radii.
Fig. 2.
Fig. 2.
The crystal packing of the molecules viewed down c axis. H atoms not involved in hydrogen bonding have been omitted for clarity.
See this image and copyright information in PMC

References

    1. Bruker (2004). APEX2 and SAINT Bruker AXS Inc., Madison, Wisconsin, USA.
    1. Cremer, D. & Pople, J. A. (1975). J. Am. Chem. Soc.97, 1354–1358.
    1. Farrugia, L. J. (1997). J. Appl. Cryst.30, 565.
    1. Harris, L. S. & Uhle, F. C. (1960). J. Pharmacol. Exp. Ther.128, 353–363. - PubMed
    1. Ho, C. Y., Haegman, W. E. & Perisco, F. (1986). J. Med. Chem.29, 118–121.