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Clinical Trial
. 2011 Sep;35(9):1415-20.
doi: 10.1007/s00264-011-1274-y. Epub 2011 May 17.

First experiences with negative pressure wound therapy and instillation in the treatment of infected orthopaedic implants: a clinical observational study

Burkhard Lehner  1 , Wim Fleischmann, Rolf Becker, Gerrolt N Jukema
Affiliations
Clinical Trial

First experiences with negative pressure wound therapy and instillation in the treatment of infected orthopaedic implants: a clinical observational study

Burkhard Lehner et al. Int Orthop. 2011 Sep.

Abstract

Purpose: Infections associated with orthopaedic implants remain a serious complication. The main objective in acute infection control is component retention, whereas this option is usually not considered for chronic infections.

Methods: This multi-centre prospective, non-randomised observational study investigated one possible treatment option for implant retention in combination with negative pressure wound therapy with instillation (NPWTi). Thirty-two patients with an infected orthopaedic implant were analysed. Twenty-two patients had an acute infection (< 8 weeks after implantation) and ten patients had a chronic infection (> 8 weeks and < 36 weeks after implant placement). Polyhexanide was used as the instillation solution in 31 of the 32 cases.

Results: Nineteen patients (86.4%) with an acute infection and eight patients (80%) with a chronic infection retained their implant at 4-6 months follow-up after treatment.

Conclusions: Our study showed that NPWTi can be used as adjunctive therapy for salvage of acutely infected orthopaedic implants and may even be considered for early chronically infected implants.

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Figures

Fig. 1
Fig. 1
CONSORT Statement 2010 flow diagram
See this image and copyright information in PMC

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