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. 2012 Jan;85(1):67-79.
doi: 10.1007/s00420-011-0643-6. Epub 2011 May 17.

The role of psychosocial stress at work for the development of cardiovascular diseases: a systematic review

Eva-Maria Backé  1 , Andreas Seidler, Ute Latza, Karin Rossnagel, Barbara Schumann
Affiliations

The role of psychosocial stress at work for the development of cardiovascular diseases: a systematic review

Eva-Maria Backé et al. Int Arch Occup Environ Health. 2012 Jan.

Abstract

Purpose: A systematic review was carried out to assess evidence for the association between different models of stress at work, and cardiovascular morbidity and mortality.

Methods: A literature search was conducted using five databases (MEDLINE, Cochrane Library, EMBASE, PSYNDEX and PsycINFO). Inclusion criteria for studies were the following: self-reported stress for individual workplaces, prospective study design and incident disease (myocardial infarction, stroke, angina pectoris, high blood pressure). Evaluation, according to the criteria of the Scottish Intercollegiate Guidelines Network, was done by two readers. In case of disagreement, a third reader was involved.

Results: Twenty-six publications were included, describing 40 analyses out of 20 cohorts. The risk estimates for work stress were associated with a statistically significant increased risk of cardiovascular disease in 13 out of the 20 cohorts. Associations were significant for 7 out of 13 cohorts applying the demand-control model, all three cohorts using the effort-reward model and 3 out of 6 cohorts investigating other models. Most significant results came from analyses considering only men. Results for the association between job stress and cardiovascular diseases in women were not clear. Associations were weaker in participants above the age of 55.

Conclusions: In accordance with other systematic reviews, this review stresses the importance of psychosocial factors at work in the aetiology of cardiovascular diseases. Besides individual measures to manage stress and to cope with demanding work situations, organisational changes at the workplace need to be considered to find options to reduce occupational risk factors for cardiovascular diseases.

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References

    1. American Heart Association (2005) Heart disease and stroke statistics—Update 2005. http://www.americanheart.org/downloadable/heart/1105390918119HDSStats200.... Accessed 01 Sept 2010
    1. André-Petersson L, Engstrom G, Hedblad B. Social support at work and the risk of myocardial infarction and stroke in women and men. Soc Sci Med. 2007;64:830–841. doi: 10.1016/j.socscimed.2006.10.020. - DOI - PubMed
    1. Belkic KL, Landsbergis PA, Schnall PL, Baker D. Is job strain a major source of cardiovascular disease risk? Scand J Work Environ Health. 2004;30:85–128. doi: 10.5271/sjweh.769. - DOI - PubMed
    1. Bosma H, Peter R, Siegrist J, Marmot M. Two alternative job stress models and the risk of coronary heart disease. Am J Public Health. 1998;88(1):68–74. doi: 10.2105/AJPH.88.1.68. - DOI - PMC - PubMed
    1. Chandola T, Siegrist J, Marmot M. Do changes in effort-reward imbalance at work contribute to an explanation of the social gradient in angina? Occup Environ Med. 2005;62:223–230. doi: 10.1136/oem.2004.016675. - DOI - PMC - PubMed

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