Review
doi: 10.1111/j.1600-0625.2011.01282.x.
From skin to the treatment of diseases--the possibilities of iPS cell research in dermatology
Affiliations
- PMID: 21585557
- DOI: 10.1111/j.1600-0625.2011.01282.x
Item in Clipboard
Review
From skin to the treatment of diseases--the possibilities of iPS cell research in dermatology
Exp Dermatol.
2011 Jun.
Abstract
Induced pluripotent stem cells (iPSCs) can be generated from different somatic cell types through ectopic expression of a set of transcription factors. iPSCs acquire all the features of embryonic stem cells (ESCs) including pluripotency and can thus give rise to any cell type of the body. iPSCs comparable with ESCs are amenable for the correction of gene mutations by homologous recombination. Patient-derived iPSCs may thus be an ideal source for studying diseases in vitro and for treating different disorders in the clinic. In this review, we summarize recent advances and possibilities of iPSC research with focus on the field of dermatology.
© 2011 John Wiley & Sons A/S.
Similar articles
-
Evolution of induced pluripotent stem cell technology.Curr Opin Hematol. 2010 Jul;17(4):276-80. doi: 10.1097/MOH.0b013e328339f2ee. Curr Opin Hematol. 2010. PMID: 20442654 Review.
-
Induced pluripotent stem cells (iPSCs)--a new era of reprogramming.J Genet Genomics. 2010 Jul;37(7):415-21. doi: 10.1016/S1673-8527(09)60060-6. J Genet Genomics. 2010. PMID: 20659705
-
Comparison of efficiency of terminal differentiation of oligodendrocytes from induced pluripotent stem cells versus embryonic stem cells in vitro.J Biosci Bioeng. 2010 Jun;109(6):622-8. doi: 10.1016/j.jbiosc.2009.11.013. Epub 2009 Dec 14. J Biosci Bioeng. 2010. PMID: 20471604
-
An introduction to induced pluripotent stem cells.Br J Haematol. 2010 Oct;151(1):16-24. doi: 10.1111/j.1365-2141.2010.08296.x. Epub 2010 Jul 27. Br J Haematol. 2010. PMID: 20666774 Review.
-
Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts.Genes Cells. 2009 Jun;14(6):683-94. doi: 10.1111/j.1365-2443.2009.01301.x. Epub 2009 May 19. Genes Cells. 2009. PMID: 19476507
Cited by
-
Genetics and epigenetics of the skin meet deep sequence.J Invest Dermatol. 2012 Mar;132(3 Pt 2):923-32. doi: 10.1038/jid.2011.436. Epub 2012 Jan 12. J Invest Dermatol. 2012. PMID: 22237701 Free PMC article. Review.
-
Nanosecond pulsed electric fields enhance mesenchymal stem cells differentiation via DNMT1-regulated OCT4/NANOG gene expression.Stem Cell Res Ther. 2020 Jul 22;11(1):308. doi: 10.1186/s13287-020-01821-5. Stem Cell Res Ther. 2020. PMID: 32698858 Free PMC article.
-
An RNAi Screen Reveals an Essential Role for HIPK4 in Human Skin Epithelial Differentiation from iPSCs.Stem Cell Reports. 2017 Oct 10;9(4):1234-1245. doi: 10.1016/j.stemcr.2017.08.023. Epub 2017 Sep 28. Stem Cell Reports. 2017. PMID: 28966120 Free PMC article.
-
A comparative study of osteogenic differentiation human induced pluripotent stem cells and adipose tissue derived mesenchymal stem cells.Cell J. 2014 Fall;16(3):235-44. Epub 2014 Oct 4. Cell J. 2014. PMID: 24611148 Free PMC article.
-
Specimen collection for induced pluripotent stem cell research: harmonizing the approach to informed consent.Stem Cells Transl Med. 2012 May;1(5):409-21. doi: 10.5966/sctm.2012-0029. Epub 2012 May 8. Stem Cells Transl Med. 2012. PMID: 23197820 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
