Fox factors fight over T cell quiescence
- PMID: 21587312
- DOI: 10.1038/ni.2040
Fox factors fight over T cell quiescence
Abstract
The transcription factor Foxp1 helps maintain the quiescence of naive T cells by inhibiting IL-7Rα expression and diminishing signaling by the kinase Erk.
Comment on
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Transcription factor Foxp1 exerts essential cell-intrinsic regulation of the quiescence of naive T cells.Nat Immunol. 2011 Jun;12(6):544-50. doi: 10.1038/ni.2034. Epub 2011 May 1. Nat Immunol. 2011. PMID: 21532575 Free PMC article.
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