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. 2010 Jun 16;66(Pt 7):o1678.
doi: 10.1107/S1600536810018568.

5-Meth-oxy-1-(3,4,5-trimethoxy-phen-yl)-1H-indole

Thomas Blake Monroe  1 , Casey Rimland, Yasamin Moazami, Daniel S Jones, Craig A Ogle
Affiliations

5-Meth-oxy-1-(3,4,5-trimethoxy-phen-yl)-1H-indole

Thomas Blake Monroe et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

The title compound, C(18)H(19)NO(4), was prepared as an indole derivative with possible anti-mitotic properties. The planes of the indole and trimethoxy-phenyl rings make a dihedral angle of 45.35 (5)° with one another. In the crystal, mol-ecules related by a twofold screw axis exhibit arene C-H⋯arene-π inter-actions which are 3.035 (1) Å in length.

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Figures

Fig. 1.
Fig. 1.
View of the title compound (50% probability displacement ellipsoids)
Fig. 2.
Fig. 2.
Packing diagram showing the arene C—H···π interactions between molecules related by a two-fold screw axis
Fig. 3.
Fig. 3.
Synthesis scheme
See this image and copyright information in PMC

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