(3E)-3-[4-(Dimethyl-amino)-phen-yl]-1-(4-hy-droxy-phen-yl)prop-2-en-1-one
- PMID: 21588017
- PMCID: PMC3006762
- DOI: 10.1107/S1600536810024050
(3E)-3-[4-(Dimethyl-amino)-phen-yl]-1-(4-hy-droxy-phen-yl)prop-2-en-1-one
Abstract
The asymmetric unit of the title compound, C(17)H(17)NO(2), contains two crystallographically independent mol-ecules. Both mol-ecules adopt a trans configuration about the C=C bond, with the C-C=C-C fragments in the two mol-ecules twisted in opposite directions [torsion angles of 174.2 (2) and -175.8 (2)°]. The two benzene rings in each of the mol-ecules make dihedral angles of 20.21 (6) and 48.64 (4)°. In the crystal, adjacent mol-ecules are linked by O-H⋯O hydrogen bonds into infinite polymeric chains.
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References
-
- Avila, H. P., Smania, E. F., Monache, F. D. & Smania, A. Jr (2008). Bioorg. Med. Chem.16, 9790–9794. - PubMed
-
- Barbour, L. J. (2001). J. Supramol. Chem.1, 189–191.
-
- Bruker (2008). APEX2 and SAINT Bruker AXS Inc., Madison, Wisconsin, USA.
-
- Fronczek, F. R., Tanrisever, N. & Fischer, N. H. (1987). Acta Cryst. C43, 158–160.
-
- Katsori, A. M. & Hadjipavlou-Litina, D. (2009). Curr. Med. Chem.16, 1062–1081. - PubMed
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