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. 2010 Aug 18;66(Pt 9):o2339.
doi: 10.1107/S1600536810032186.

N-(4-Meth-oxy-phen-yl)-N'-(5-nitro-1,3-thia-zol-2-yl)urea

Alan J Lough, Justin W Hicks, John F Valliant, Alan A Wilson, Neil Vasdev

N-(4-Meth-oxy-phen-yl)-N'-(5-nitro-1,3-thia-zol-2-yl)urea

Alan J Lough et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

The title compound, C(11)H(10)N(4)O(4)S, is a derivative of N-(4-meth-oxy-benz-yl)-N'-(5-nitro-1,3-thia-zol-2-yl)urea (AR-A014418), a known glycogen synthase kinase 3β (GSK-3β) inhibitor. All non-H atoms in the mol-ecule are essentially coplanar, with an r.m.s. deviation of 0.045 Å and a maximum deviation of 0.115 (2) Å for the carbonyl O atom. In the crystal structure, mol-ecules are linked via N-H⋯O hydrogen bonds into one-dimensional chains along [101].

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Figures

Fig. 1.
Fig. 1.
The molecular structure of the title compound with probability ellipsoids drawn at the 30% level.
Fig. 2.
Fig. 2.
Part of the crystal structure of the title compound with hydrogen bonds drawn as dashed lines.
See this image and copyright information in PMC

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