Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Aug 25;66(Pt 9):o2388-9.
doi: 10.1107/S1600536810033520.

N-(2,5-Dimeth-oxy-phen-yl)-N'-[4-(2-hy-droxy-eth-yl)phen-yl]urea

Hyeong Choi, Yong Suk Shim, Byung Hee Han, Sung Kwon Kang, Chang Keun Sung

N-(2,5-Dimeth-oxy-phen-yl)-N'-[4-(2-hy-droxy-eth-yl)phen-yl]urea

Hyeong Choi et al. Acta Crystallogr Sect E Struct Rep Online. .

Abstract

In the title compound, C(17)H(20)N(2)O(4), the 2,5-dimeth-oxy-phenyl unit is essentially planar, with an r.m.s. deviation of 0.015 Å. The dihedral angle between the benzene rings is 43.66 (4)°. The mol-ecular structure is stabilized by a short intra-molecular N-H⋯O hydrogen bond. In the crystal, inter-molecular N-H⋯O and O-H⋯O hydrogen bonds link the mol-ecules into a three-dimensional network.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
Molecular structure of (I), showing the atom-numbering scheme and 50% probability ellipsoids. Intramolecular N—H···O bond is shown as dashed lines.
Fig. 2.
Fig. 2.
Part of the crystal structure of (I), showing 3-D network of molecules linked by intermolecular N—H···O and O—H···O hydrogen bonds.
See this image and copyright information in PMC

References

    1. Battaini, G., Monzani, E., Casella, L., Santagostini, L. & Pagliarin, R. (2000). J. Biol. Inorg. Chem.5, 262–268. - PubMed
    1. Brandenburg, K. (2010). DIAMOND Crystal Impact GbR, Bonn, Germany.
    1. Briganti, S., Camera, E. & Picardo, M. (2003). Pigm. Cell Res.16, 101–110. - PubMed
    1. Bruker (2002). SAINT and SMART Bruker AXS Inc., Madison, Wisconsin, USA.
    1. Cabanes, J., Chazarra, S. & Garcia-Carmona, F. (1994). J. Pharm. Pharmacol.46, 982–985. - PubMed