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. 1990 Jun;64(6):3139-43.
doi: 10.1128/JVI.64.6.3139-3143.1990.

Isolation of a possible archetypal JC virus DNA sequence from nonimmunocompromised individuals

Y Yogo  1 , T Kitamura, C Sugimoto, T Ueki, Y Aso, K Hara, F Taguchi
Affiliations

Isolation of a possible archetypal JC virus DNA sequence from nonimmunocompromised individuals

Y Yogo et al. J Virol. 1990 Jun.

Abstract

We molecularly cloned JC polyomavirus DNAs from urine samples of eight nonimmunosuppressed patients and two healthy individuals. The cloned viral DNAs all contained an archetypal regulatory sequence from which various regulatory sequences of JC polyomavirus isolates derived from patients with progressive multifocal leukoencephalopathy could have evolved by deletion and amplification.

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