Biofilms and infectious diseases: biology to mathematics and back again

Abstract

There has been tremendous growth in biofilm research in the past three decades. This growth has been reflected in development of a wide variety of experimental, clinical, and theoretical techniques fostered by our increased knowledge. Keeping the theoretical developments abreast of the experimental advancements and ensuring that the theoretical results are disseminated to the experimental and clinical community is a major challenge. This manuscript provides an overview of recent developments in each scientific domain. More importantly, this manuscript aims to identify areas where the theory lags behind the experimental understanding (and vice versa). The major themes of the manuscript derive from discussions and presentations at a recent interdisciplinary workshop that brought together a variety of scientists whose underlying studies focus on biofilm processes.