Autoimmune disease: Blocking the drivers

Comment

Sarah Crunkhorn. Nat Rev Drug Discov. 2011 Jun.

. 2011 Jun;10(6):413.

doi: 10.1038/nrd3467. Epub 2011 May 20.

No abstract available

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Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity.
Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, Rastinejad F, Littman DR. Huh JR, et al. Nature. 2011 Apr 28;472(7344):486-90. doi: 10.1038/nature09978. Epub 2011 Mar 27. Nature. 2011. PMID: 21441909 Free PMC article.
Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand.
Solt LA, Kumar N, Nuhant P, Wang Y, Lauer JL, Liu J, Istrate MA, Kamenecka TM, Roush WR, Vidović D, Schürer SC, Xu J, Wagoner G, Drew PD, Griffin PR, Burris TP. Solt LA, et al. Nature. 2011 Apr 28;472(7344):491-4. doi: 10.1038/nature10075. Epub 2011 Apr 17. Nature. 2011. PMID: 21499262 Free PMC article.