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Review
. 2011 Jun:38 Suppl 2:S11-6.
doi: 10.1053/j.seminoncol.2011.04.005.

Other options in the treatment of advanced breast cancer

Melody A Cobleigh  1
Affiliations
Review

Other options in the treatment of advanced breast cancer

Melody A Cobleigh. Semin Oncol. 2011 Jun.

Abstract

Many cytotoxic therapies are available for patients with metastatic breast cancer, but response rates are low and acquired or de novo resistance is virtually universal. Among the agents that are used in the treatment of pretreated metastatic breast cancer are vinorelbine, gemcitabine, nab-paclitaxel, pemetrexed, platinum salts (eg, cisplatin, carboplatin), pegylated liposomal doxorubicin, etoposide, and irinotecan. Therapies that improve overall survival in patients with anthracycline- and taxane-resistant metastatic breast cancer are needed.

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