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Review
. 2011 Jun;32(6):716-20.
doi: 10.1038/aps.2011.59. Epub 2011 May 23.

Maternal-fetal fluid balance and aquaporins: from molecule to physiology

Xiao-yan Sha  1 , Zheng-fang Xiong, Hui-shu Liu, Xiao-dan Di, Tong-hui Ma
Affiliations
Review

Maternal-fetal fluid balance and aquaporins: from molecule to physiology

Xiao-yan Sha et al. Acta Pharmacol Sin. 2011 Jun.

Abstract

Maternal-fetal fluid balance is critical during pregnancy, and amniotic fluid is essential for fetal growth and development. The placenta plays a key role in a successful pregnancy as the interface between the mother and her fetus. Aquaporins (AQPs) form specific water channels that allow the rapid transcellular movement of water in response to osmotic/hydrostatic pressure gradients. AQPs expression in the placenta and fetal membranes may play important roles in the maternal-fetal fluid balance.

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Figures

Figure 1
Figure 1
AQPs expression in pregnant female mammalian reproductive system.
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