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. 2008 Fall;8(3):140-5.

Infliximab-associated Chiasmopathy

Erin Farrell  1 , Joel G Sacks
Affiliations

Infliximab-associated Chiasmopathy

Erin Farrell et al. Ochsner J. 2008 Fall.

Abstract

Optic neuropathy has been reported in association with the use of tumor necrosis factor-alpha antagonists such as etanercept, infliximab, and adalimumab. This is a report of a patient who began experiencing decreased vision approximately 1 month after starting infliximab therapy for rheumatoid arthritis. Visual field testing showed bitemporal hemianopic scotomas, indicating involvement of the nerve fibers in the optic chiasm. The infliximab was discontinued, and the patient experienced substantial improvement in her visual acuity and visual field.

Keywords: infliximab; optic neuropathy.

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Figures

Figure 1a
Figure 1a. (right eye) and 1b (left eye): Examination results from initial presentation.
Figure 2a
Figure 2a. (right eye) and 2b (left eye): Examination results 2 months after presentation.
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See this image and copyright information in PMC

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