Hidalgo, I. J., Raub, T. J., and Borchardt, R. T.: Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability, Gastroenterology, 96, 736-749, 1989--the backstory

Affiliations

Comment

Ronald T Borchardt. AAPS J. 2011 Sep.

. 2011 Sep;13(3):323-7.

doi: 10.1208/s12248-011-9283-8. Epub 2011 May 24.

¹ Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, 66047, USA. rborchardt@ku.edu

No abstract available

Comment on

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability.
Hidalgo IJ, Raub TJ, Borchardt RT. Hidalgo IJ, et al. Gastroenterology. 1989 Mar;96(3):736-49. Gastroenterology. 1989. PMID: 2914637

1. Audus KA, Borchardt RT. Characterization of an in vitro blood–brain barrier model system for studying drug transport and metabolism. Pharm Res. 1986;3:81–87. doi: 10.1023/A:1016337202335. - DOI - PubMed
1. Osiecka I, Borchardt RT, Fix JA, Gardner CA, Porter PA. In vitro drug absorption models. I. Brush border membrane vesicles, isolated mucosal cells and everted intestinal rings: characterization and salicylate accumulation. Pharm Res. 1985;2:284–293. doi: 10.1023/A:1016341601273. - DOI - PubMed
1. Porter PA, Osiecka I, Borchardt RT, Fix JA, Frost L, Gardner CA. In vitro drug absorption models. II. Salicylate, cefoxitin, α-methyldopa and theophylline uptake in cells and rings: correlation with in vivo bioavailability. Pharm Res. 1985;2:293–298. doi: 10.1023/A:1016393618111. - DOI - PubMed
1. Osiecka I, Cortese M, Porter PA, Borchardt RT, Fix JA, Gardner CR. Intestinal absorption of α-methyldopa: in vitro mechanistic studies in rat small intestinal segments. J Pharmacol Exp Ther. 1987;242:443–449. - PubMed
1. Leibovitz A, Stinson JC, McCombs WB, McCoy CE, Mazur KC, Mabry ND. Classification of human colorectal adenocarcinoma cell line. Cancer Res. 1976;36:4562–4569. - PubMed